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Essentially, L-DOPA is transported across the blood brain barrier by LAT-1 (L or Large amino acid transporter). This transporter moves amino acids like phenylalanine and tyrosine across the blood brain barrier. Without a transporter, a molecule needs to be lipid soluble to cross the blood brain barrier.
Most common side effects associated with this drug involve erythroderma, scaly skin, urticaria, itching, and acneiform eruptions. A very serious allergic reaction is not likely to occur. This is not a complete list of all possible side effects. Others may occur in some patients and there may be some side effects not known yet. In case you have experienced any side effect not listed above, immediately notify your doctor or local poison centre.
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Tell your doctor if you are pregnant or plan on getting pregnant. You will need to talk about the benefits and risks of using this medicine while you are pregnant. Tell your doctor if you are breast-feeding. You will need to talk about any risks to your baby. -
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