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    How long does it take for Sumatriptan to work? Oral tablets: onset of migraine relief generally begins after 30 minutes of dosing and peaks 2 to 4 hours thereafter. Nasal spray: onset of headache relief occurs after 15-30 minutes
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    BRAND NAME: Imitrex, Alsuma, Imitrex STATdose System, Sumavel DosePro. DRUG CLASS AND MECHANISM: Sumatriptan is a drug that is used for treating migraine headaches. It belongs to a class of drugs called selective serotonin receptor agonists.
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    Sub-Q injection: 10-15 minutes; maximum headache relief is attained within 90 minutes to 2 hours. How long does Imitrex stay in the system? The half life is 1.5�2.6 hours. It takes about 7.5-15.6 hours for sumatriptan to clear out of the system.
    Sumatriptan belongs to a class of drugs known as triptans. It affects a certain natural substance (serotonin) that causes narrowing of blood vessels in the brain. It may also relieve pain by affecting certain nerves in the brain.Sumatriptan does not prevent future migraines or lessen how often you get migraine attacks.

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