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Avoid taking iron supplements or eating a diet that is high in protein (protein sources include meat, eggs, and cheese). These things can make it harder for your body to digest and absorb carbidopa and levodopa. Talk with your doctor or nutrition counselor about the best foods to eat while you are taking this medication. If you are unsure of how this medicine will affect you, be careful if you drive or do anything that requires you to be awake and alert.
Uses of Sinemet: It is used to treat Parkinson’s disease. It is used to treat signs like Parkinson’s disease caused by other health problems. It may be given to you for other reasons. Talk with the doctor.
When carbidopa and levodopa are administered together, the half-life of levodopa is increased to about 1.5 hours. At steady state, the bioavailability of carbidopa from SINEMET tablets is approximately 99% relative to the concomitant administration of carbidopa and levodopa.
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This medicine may “wear off” as the time for your next dose gets closer. Tell your doctor if this happens and it bothers you. Talk with your doctor before you drink alcohol or use other drugs and natural products that slow your actions. The chance of a type of skin cancer called melanoma may be raised in people with Parkinson’s disease. It is not known if this medicine may also raise the chance. Have skin exams while you take Sinemet. Talk with your doctor. A dark color (red, brown, or black) may show up in your saliva, urine, or sweat. This is not harmful but may discolor your clothes.
Neuroleptic malignant syndrome (NMS) is a very bad and sometimes deadly health problem that has happened when this medicine was stopped all of a sudden. NMS has also happened when the dose of Sinemet was lowered. Call your doctor right away if you have any fever, muscle cramps or stiffness, dizziness, very bad headache, confusion, change in thinking, fast heartbeat, heartbeat that does not feel normal, or are sweating a lot.
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