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August 4, 2018 at 3:58 am #59456
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The pump acts to re-absorb sodium and water in exchange for potassium, which is then eliminated in the urine. Consequently, aldosterone antagonism can cause hyperkalemia. Hyperkalemia is an established adverse effect of both spironolactone and eplerenone. The symptoms of hyperkalemia begin with muscle weakness.
No, Spironolactone is an aldosterone blocking agent blocking the effects of the adrenal hormone Aldosterone that is part of the renin angiotensin system, inducing water and salt retention, thus causing water overload and maybe high blood pressure
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Aldactone (spironolactone) is an aldosterone receptor antagonist that causes the kidneys to remove water and sodium from the body, with reduced losses of potassium. Aldactone is used to reduce edema caused by heart, liver or kidney problems, hypertension, and certain patients with hyperaldosteronism. -
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