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05.10.2006 · Hi,Can someone please tell me if Accutane slows down your metabolism or ruins your thyroid gland? I’ve been 1… By CTU309 in Accutane (isotretinoin) logsProfessional guide for ISOtretinoin (Systemic … Enhanced with a high-fat … they are bioequivalent when taken with a high-fat meal. Metabolism …05.05.2010 · 1.7 Fat metabolism and absorbtion. … Isotretinoin significantly reduced the fat elimination … Vahlquist A, Vessby B. Plasma fat elimination tissue …Isotretinoin treatment alters the plasma lipid levels but the mechanisms and the effects on the metabolism of triglyceride-rich lipoproteins such as …