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This eMedTV page explains that there are some situations where you should temporarily stop taking metformin; contrast medium use is one of them. This page …Almost every medical student and doctor will tell you that metformin and IV contrast don’t mix. Most of us; however, probably don’t fully understand why …Patients receiving IV iodinated contrast media prior to CT or X-rays to improve visibility of the results. Special considerations are required for patients …Contrast media and metformin. Guidelines to diminish the risk of lactic acidosis in non-insulin dependent diabetics after administration of contrast media.